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发布时间:2024-02-04 16:54   咨询量:
  • 英文名称:anti- Vimentin antibody
  • 产品货号: FNab09410
  • 适应种属:人源,大鼠,小鼠
  • 宿主:小鼠
  • 亚型: IgG1
  • 验证应用: ELISA, WB, IHC
  • 简介:菲恩生物抗Vimentin抗体经SDS-PAGE分析,纯度大于95%,采用蛋白A/G柱纯化方法,为用户提供高亲和力、高特异性的优质抗体。
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    产品详情
    名称:anti- Vimentin antibody
    货号: FNab09410
    适应种属:人源,大鼠,小鼠
    规格:100ug(微克)
    状态:液体
    纯化方法:蛋白A/G柱纯化
    纯度:经SDS-PAGE分析,纯度大于95%
    宿主:小鼠
    亚型: IgG1
    存储:用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融)
    免疫原: vimentin
    免疫原别称: FLJ36605 antibody, VIM antibody, Vimentin antibody
    分子量: 55 kDa
    验证应用: ELISA, WB, IHC
    建议稀释比例: WB: 1:1000-1:10000; IHC: 1:200-1:2000; IF: 1:20-1:200
    UniProt ID: P08670
    克隆性:单克隆
    背景介绍:Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha(TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10(124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.
    图像:     Vimentin抗体
    Immunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using FNab09410(Vimentin Antibody) at dilution of 1:500。
        anti- Vimentin antibody
    Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09410(Vimentin Antibody) at dilution of 1:2000。
    

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