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发布时间：2023-09-08 16:07 咨询量：
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产品详情
| 名称： | anti- RPS3 antibody |
|---|---|
| 货号： | FNab07476 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | ribosomal protein S3 |
| 分子量： | 26.7 kDa |
| 验证应用： | ELISA, WB, IHC |
| 建议稀释比例： | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| UniProt ID： | P23396 |
| 克隆性： | 多克隆 |
| 背景介绍： | Involved in translation as a component of the 40S small ribosomal subunit(PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA(PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA(PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine(8-oxoG), a common DNA lesion caused by reactive oxygen species(ROS)(PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA(PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1(PubMed:15518571). Enhances the uracil excision activity of UNG1(PubMed:18973764). |
| 图像： |  Immunohistochemistry of paraffin-embedded human ovary tumor using FNab07476(RPS3 antibody) at dilution of 1:50。
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