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发布时间:2023-08-31 09:46   咨询量:
  • 英文名称: anti- RAD51 antibody
  • 产品货号: FNab07079
  • 适应种属:人源,大鼠,小鼠
  • 宿主:兔
  • 亚型:lgG
  • 验证应用: ELISA, WB, IP,IHC
  • 简介:菲恩生物抗RAD51抗体经SDS-PAGE分析,纯度大于95%,采用免疫亲和纯化方法,为用户提供高亲和力、高特异性的优质抗体。
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    产品详情
    名称: anti- RAD51 antibody
    货号: FNab07079
    适应种属:人源,大鼠,小鼠
    规格:100ug(微克)
    状态:液体
    纯化方法:免疫亲和纯化
    纯度:经SDS-PAGE分析,纯度大于95%
    宿主:
    亚型:lgG
    存储:用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融)
    免疫原: RAD51 homolog
    免疫原别称: RAD51A antibody, RECA antibody
    分子量: 37 kDa
    验证应用: ELISA, WB, IP,IHC
    建议稀释比例: WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500
    UniProt ID: Q06609
    克隆性:多克隆
    背景介绍:Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
    图像:RAD51抗体
    Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab07079(RAD51 Antibody) at dilution of 1:200。

    RAD51抗体
    IP Result of anti-RAD51 (IP:FNab07079, 3ug; Detection:FNab07079 1:1000) with mouse testis tissue lysate 4000ug。


         anti- RAD51 antibody
    HeLa cells were subjected to SDS PAGE followed by western blot with FNab07079(RAD51 Antibody) at dilution of 1:1000。

    

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