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发布时间：2023-08-30 14:20 咨询量：
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产品详情
| 名称： | anti- PARP1 antibody |
|---|---|
| 货号： | FNab09939 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 蛋白A/G柱纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 小鼠 |
| 亚型： | IgG1 |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | poly (ADP-ribose) polymerase 1 |
| 免疫原别称： | ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, pADPRT 1 antibody, PARP antibody, PARP 1 antibody, PARP1 antibody, poly (ADP ribose) polymerase 1 antibody, Poly [ADP ribose] polymerase 1 antibody, Poly[ADP ribose] synthase 1 antibody, PPOL an |
| 分子量： | 115 kDa, 89 kDa |
| 验证应用： | ELISA, WB, IHC, IF |
| 建议稀释比例： | WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500 |
| UniProt ID： | P09874 |
| 克隆性： | 单克隆 |
| 背景介绍： | PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis. |
| 图像： |  Immunofluorescent analysis of HeLa cells using FNab09939 (PARP1 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L)。
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